Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | MAT2A | P31153 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490769 | 0.80 | NFE2L2 (0.56) | KCNH2MAT2AKMT2AALDH1A1MEN1 | |
| SCHEMBL5490767 | 0.80 | NFE2L2 (0.56) | KCNH2MAT2AKMT2AALDH1A1MEN1 | |
| SCHEMBL17083049 | 0.79 | KCNH2 (0.51) | KCNH2MAT2AKMT2AALDH1A1MEN1 | |
| SCHEMBL9680696 | 0.76 | IDO1 (0.42) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL443909 | 0.76 | IDO1 (0.42) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL443908 | 0.76 | IDO1 (0.42) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL9680702 | 0.76 | IDO1 (0.42) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL18589846 | 0.76 | KCNH2 (0.49) | KCNH2MAT2AKMT2AALDH1A1MEN1 | |
| SCHEMBL9680244 | 0.75 | IDO1 (0.68) | ALDH1A1MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL9680249 | 0.75 | IDO1 (0.68) | ALDH1A1MAPTKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017078927-A1 | ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2017-05-11 | — | — | WO | disclosed |