Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18844361 | 0.82 | MAPT (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL16156047 | 0.80 | MAPT (0.46) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL5319788 | 0.75 | ALDH1A1 (0.54) | SMN1; SMN2HDAC1HDAC3HDAC6HDAC10 | |
| SCHEMBL30640552 | 0.74 | KDR (0.61) | CHRM1HDAC1HDAC3HDAC6HDAC10 | |
| SCHEMBL27843675 | 0.74 | MEN1 (0.67) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL31215050 | 0.74 | MEN1 (0.80) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL892659 | 0.74 | SCD (0.53) | MAPTSMN1; SMN2HDAC1HDAC3HDAC6 | |
| SCHEMBL21339930 | 0.72 | CHRM1 (0.52) | CHRM1HDAC1HDAC3HDAC6HDAC10 | |
| SCHEMBL2185599 | 0.72 | CNR2 (0.51) | SCD | |
| SCHEMBL22926122 | 0.71 | POLB (0.47) | NPC1RAB9ASMN1; SMN2CHRM1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170129863-A1 | IMINOSYDNONE DERIVATIVES FOR CONJUGATION AND RELEASE OF COMPOUNDS OF INTEREST | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129863-A1 | IMINOSYDNONE DERIVATIVES FOR CONJUGATION AND RELEASE OF COMPOUNDS OF INTEREST | IPO5, IDE, IMPDH1 | MEN1 233/4885KMT2A 4239/4885NPC1 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.