Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19560634 | 0.89 | CASP2 (0.56) | CASP2HPGDNAAAFAAHDNM1 | |
| SCHEMBL13655544 | 0.86 | FAAH (0.57) | CASP2HPGDNAAAFAAHALDH1A1 | |
| SCHEMBL13655533 | 0.86 | FAAH (0.57) | CASP2HPGDNAAAFAAHALDH1A1 | |
| SCHEMBL13655575 | 0.86 | FAAH (0.57) | CASP2HPGDNAAAFAAHALDH1A1 | |
| SCHEMBL13655546 | 0.86 | FAAH (0.57) | CASP2HPGDNAAAFAAHALDH1A1 | |
| SCHEMBL22184083 | 0.85 | CASP2 (0.41) | CASP2NAAACTSDFAAHALDH1A1 | |
| SCHEMBL16800946 | 0.84 | MEN1 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL13695963 | 0.82 | CASP2 (0.41) | CASP2HPGD | |
| SCHEMBL30377114 | 0.82 | CASP2 (0.41) | CASP2HPGD | |
| SCHEMBL24193112 | 0.81 | SMN1; SMN2 (0.40) | CASP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017078623-A1 | BACKGROUND-FREE FLUORESCENT PROBES FOR LIVE CELL IMAGING | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2017-05-11 | — | — | WO | disclosed |