Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.54 |
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655544 | 1.00 | FAAH (0.57) | FAAHDNM1CASP2NAAALPAR1 | |
| SCHEMBL13655546 | 1.00 | FAAH (0.57) | FAAHDNM1CASP2NAAALPAR1 | |
| SCHEMBL13655533 | 1.00 | FAAH (0.57) | FAAHDNM1CASP2NAAALPAR1 | |
| SCHEMBL16369373 | 0.92 | FAAH (0.58) | FAAHDNM1CASP2NAAALPAR1 | |
| SCHEMBL13655534 | 0.91 | EPHX2 (0.62) | LPAR1EPHX2LPAR2CNR1ALDH1A1 | |
| SCHEMBL16328587 | 0.87 | CASP2 (0.62) | FAAHDNM1CASP2NAAAEPHX2 | |
| SCHEMBL13651623 | 0.87 | FAAH (0.49) | FAAHDNM1CASP2NAAALPAR1 | |
| SCHEMBL20009458 | 0.87 | CASP2 (0.58) | FAAHDNM1CASP2NAAALPAR1 | |
| SCHEMBL18845127 | 0.86 | CASP2 (0.50) | FAAHDNM1CASP2NAAAALDH1A1 | |
| SCHEMBL17122488 | 0.85 | CASP2 (0.56) | FAAHDNM1CASP2NAAALPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9351491-B2 | Inhibition and dispersion of biofilms in plants with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-05-31 | — | — | US | disclosed |
| US-9145395-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-9145395-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-9145395-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-20130315874-A1 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-11-28 | — | — | US | disclosed |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2013-05-23 | — | — | US | disclosed |
| US-8367713-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367713-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-02-05 | — | — | US | disclosed |
| US-20110117158-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | MELANDER CHRISTIAN | 2011-05-19 | — | — | US | disclosed |
| US-7897631-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897631-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897631-B2 | Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-01 | — | — | US | disclosed |
| WO-2010077603-A1 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2009131654-A2 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009131654-A2 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | WO | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263438-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | TFPI, O60361, TFPI2 | FAAH 4397/4885DNM1 576/4885CASP2 1455/4885 |
| US-20110117158-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | TFPI, O60361, TFPI2 | FAAH 4397/4885DNM1 576/4885CASP2 1455/4885 |
| US-20130129795-A1 | INHIBITION AND DISPERSION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | TFPI, O60361, TFPI2 | FAAH 4397/4885DNM1 576/4885CASP2 1455/4885 |
| US-20130315874-A1 | INHIBITION AND DISPERSION OF BIOFILMS IN PLANTS WITH IMIDAZOLE-TRIAZOLE DERIVATIVES | SOD1, APOBEC3A, CLPP | FAAH 3517/4885DNM1 530/4885CASP2 2724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.