SCHEMBL18845451

SCHEMBL18845451

CCCCC[N+]12CC[N+](CCCCC)(CC1)CC2

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
THRB P10828 1/20 0.41
LMNA P02545 3/20 0.35
GNAI3 P08754 1/20 0.35
GNAO1 P09471 1/20 0.35
GNAI1 P63096 1/20 0.35
SLC22A1 O15245 3/20 0.33
SLC22A2 O15244 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DNM1 Q05193 5/20 0.32
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL22788428 0.94 TSHR (0.44) TSHRTHRBLMNAGNAI3GNAO1
SCHEMBL4905037 0.90 TSHR (0.38) TSHRTHRBLMNAALDH1A1
SCHEMBL14050667 0.85 LMNA (0.52) TSHRTHRBLMNAGNAI3GNAO1
SCHEMBL9208462 0.85 TSHR (0.36) TSHRTHRBGNAI3GNAO1GNAI1
SCHEMBL4065896 0.82 TSHR (0.32) TSHRTHRBGNAI3GNAO1GNAI1
SCHEMBL17975048 0.82 TSHR (0.33) TSHRTHRBGNAI3GNAO1GNAI1
SCHEMBL16706067 0.82 TSHR (0.33) TSHRTHRBGNAI3GNAO1GNAI1
SCHEMBL4067401 0.80 TSHR (0.36) TSHRTHRBGNAI3GNAO1GNAI1
SCHEMBL868069 0.80 GNAI3 (0.41) TSHRTHRBGNAI3GNAO1GNAI1
SCHEMBL2525998 0.80 GNAI3 (0.41) TSHRTHRBGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9873116-B2 Ion exchange membrane, method for manufacturing same, module, and device FUJIFILM CORPORATION (JP) 2018-01-23 US disclosed
US-20170128931-A1 ION EXCHANGE MEMBRANE, METHOD FOR MANUFACTURING SAME, MODULE, AND DEVICE FUJIFILM CORPORATION (JP) 2017-05-11 US disclosed