Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 18/20 | 0.61 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18023290 | 0.97 | KDM1A (0.61) | KDM1ACTSBHPGDS | |
| SCHEMBL18848695 | 0.94 | KDM1A (0.54) | KDM1ACTSB | |
| SCHEMBL18848748 | 0.89 | CTSB (0.58) | KDM1ACTSBHPGDS | |
| SCHEMBL16455202 | 0.88 | KDM1A (0.65) | KDM1A | |
| SCHEMBL16455072 | 0.88 | KDM1A (0.60) | KDM1ACTSBHPGDS | |
| SCHEMBL18848471 | 0.88 | CTSB (0.57) | KDM1ACTSBHPGDS | |
| SCHEMBL18016675 | 0.86 | KDM1A (0.61) | KDM1A | |
| SCHEMBL18848468 | 0.86 | CTSB (0.55) | KDM1ACTSBHPGDS | |
| SCHEMBL18023305 | 0.85 | KDM1A (0.65) | KDM1A | |
| SCHEMBL18023343 | 0.83 | KDM1A (0.69) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017079753-A1 | LYSINE-SPECIFIC HISTONE DEMETHYLASE AS A NOVEL THERAPEUTIC TARGET IN MYELOPROLIFERATIVE NEOPLASMS | IMAGO BIOSCIENCES, INC. (US) | 2017-05-11 | — | — | WO | disclosed |