Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402766 | 0.86 | HDAC1 (0.62) | EPHX2NR1H4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2344164 | 0.81 | ALDH1A1 (0.71) | EPHX2NR1H4RAB9ASMN1; SMN2LMNA | |
| SCHEMBL5690964 | 0.78 | HDAC1 (0.72) | EPHX2NR1H4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14615882 | 0.76 | RAB9A (0.68) | EPHX2NR1H4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10606216 | 0.75 | EPHX2 (0.65) | EPHX2NR1H4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15149873 | 0.75 | KCNK9 (0.60) | EPHX2NR1H4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24534543 | 0.75 | HDAC1 (0.56) | EPHX2NR1H4RAB9ASMN1; SMN2LMNA | |
| SCHEMBL20100374 | 0.75 | HDAC1 (0.56) | EPHX2NR1H4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24241673 | 0.74 | RAB9A (0.57) | EPHX2NR1H4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5909057 | 0.74 | CA12 (0.58) | RAB9ANPC1LMNAL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968571-B2 | Inhibitors and methods of inhibiting bacterial and viral pathogens | SIGA TECHNOLOGIES, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-20170128393-A1 | INHIBITORS AND METHODS OF INHIBITING BACTERIAL AND VIRAL PATHOGENS | SIGA TECHNOLOGIES, INC. (US) | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170128393-A1 | INHIBITORS AND METHODS OF INHIBITING BACTERIAL AND VIRAL PATHOGENS | TST, TPMT, EIF2AK2 | EPHX2 3896/4885NR1H4 2157/4885RAB9A 2327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.