Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.42 |
| ▸ | PPARA | Q07869 | 10/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | BRD1 | O95696 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18851080 | 0.84 | PPARG (0.48) | PPARGPPARAPPARDMTNR1BALDH3A1 | |
| SCHEMBL18851582 | 0.84 | PPARG (0.46) | PPARGPPARAPPARDMTNR1BALDH3A1 | |
| SCHEMBL18850580 | 0.82 | PPARG (0.43) | PPARGPPARAPPARDMTNR1BALDH3A1 | |
| SCHEMBL18824246 | 0.80 | PPARG (0.47) | PPARGPPARAPPARDMTNR1BALDH3A1 | |
| SCHEMBL18851390 | 0.78 | PPARG (0.39) | PPARGPPARAPPARDMTNR1BALDH1A1 | |
| SCHEMBL18824208 | 0.74 | NOD2 (0.47) | PPARGPPARAPPARDMTNR1BALDH3A1 | |
| SCHEMBL3525871 | 0.69 | PPARG (0.59) | PPARGPPARAPPARDMTNR1B | |
| SCHEMBL18851072 | 0.67 | ACLY (0.40) | ALDH3A1 | |
| SCHEMBL4657662 | 0.66 | PPARG (0.70) | PPARGPPARAPPARDNOD2NOD1 | |
| SCHEMBL3523667 | 0.66 | PPARG (0.76) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017075694-A1 | ANTIBIOTIC COMPOUNDS, PHARMACEUTICAL FORMULATIONS THEREOF AND METHODS AND USES THEREFOR | SIMON FRASER UNIVERSITY (CA) | 2017-05-11 | — | — | WO | disclosed |