Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25101188 | 0.81 | LMNA (0.68) | LMNAMAPK14KDM4CIDO1MAPT | |
| SCHEMBL15150030 | 0.80 | RECQL (0.66) | LMNAKDM4CTDP1L3MBTL1RECQL | |
| SCHEMBL5262315 | 0.80 | LMNA (0.62) | LMNAMAPK14KDM4CIDO1 | |
| SCHEMBL10733172 | 0.78 | LMNA (1.00) | LMNAKDM4CMAPTMAPK1TDP1 | |
| SCHEMBL6641884 | 0.73 | IDO1 (0.60) | LMNAMAPK14KDM4CIDO1MAPT | |
| SCHEMBL2465344 | 0.71 | LMNA (0.51) | LMNAMAPK14MAPTMAPK1TDP1 | |
| SCHEMBL2433371 | 0.71 | RECQL (0.53) | LMNAHPGDMAPTMAPK1TDP1 | |
| SCHEMBL13195026 | 0.70 | LTA4H (0.49) | MAPK14LTA4H | |
| SCHEMBL18989127 | 0.70 | LMNA (0.47) | LMNAHPGDMAPTTDP1L3MBTL1 | |
| SCHEMBL24096443 | 0.69 | LMNA (0.46) | LMNAMAPK14KDM4CMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017076349-A1 | LONG-ACTING DIPEPTIDYL PEPTIDASE-IV INHIBITOR, APPLICATION THEREOF, AND PREPARATION METHOD THEREFOR | 四川科伦博泰生物医药股份有限公司 | 2017-05-11 | — | — | WO | disclosed |