Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532625 | 0.88 | SRD5A2 (0.55) | LMNASRD5A2ALDH1A1FOLH1SRD5A1 | |
| SCHEMBL11532467 | 0.78 | RHEB (0.55) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11531739 | 0.75 | KDM4E (0.45) | SRD5A2ALDH1A1SRD5A1MAPTCYP2C19 | |
| SCHEMBL11538794 | 0.75 | RXRA (0.49) | LMNASRD5A2ALDH1A1FOLH1SRD5A1 | |
| SCHEMBL2465344 | 0.75 | LMNA (0.51) | LMNASRD5A2FOLH1MAPTSMN1; SMN2 | |
| SCHEMBL11607595 | 0.74 | PTGER1 (0.46) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10592075 | 0.72 | SRD5A2 (0.58) | LMNASRD5A2ALDH1A1FOLH1SRD5A1 | |
| SCHEMBL341109 | 0.71 | SGMS2 (0.62) | LMNAALDH1A1FOLH1MEN1KMT2A | |
| SCHEMBL11519443 | 0.71 | FOLH1 (0.57) | SRD5A2ALDH1A1FOLH1MEN1KMT2A | |
| SCHEMBL29557477 | 0.71 | HPGD (0.59) | LMNAMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017105565-A2 | COMPOSITIONS FOR THERAPEUTICS, TARGETED PET IMAGING AND METHODS OF THEIR USE | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2017-06-22 | — | — | WO | disclosed |