Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 7/20 | 0.50 |
| ▸ | HEXB | P07686 | 7/20 | 0.50 |
| ▸ | DHFR | P00374 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1889973 | 0.98 | HEXA (0.49) | HEXAHEXBDHFRMEN1KMT2A | |
| SCHEMBL12368257 | 0.88 | HEXA (0.64) | HEXAHEXBDHFRMEN1KMT2A | |
| SCHEMBL4526810 | 0.85 | HEXA (0.47) | HEXAHEXBDHFRMEN1KMT2A | |
| SCHEMBL11593238 | 0.85 | KMT2A (0.63) | HEXAHEXBDHFRMEN1KMT2A | |
| SCHEMBL12368258 | 0.85 | HEXA (0.47) | HEXAHEXBDHFRMEN1KMT2A | |
| SCHEMBL3500167 | 0.84 | DHFR (0.61) | HEXAHEXBDHFRKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4537159 | 0.83 | HEXA (0.46) | HEXAHEXBDHFRMEN1KMT2A | |
| SCHEMBL14358933 | 0.82 | HEXA (0.65) | HEXAHEXBDHFRALDH1A1CYP2D6 | |
| SCHEMBL12368254 | 0.80 | HEXA (0.64) | HEXAHEXBDHFRALDH1A1 | |
| SCHEMBL1882625 | 0.78 | MAP4K4 (0.57) | HEXAHEXBDHFRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110256092-A1 | QUINOLINE DERIVATIVES FOR MODULATING DNA METHYLATION | SUPERGEN, INC. (US) | 2011-10-20 | — | — | US | disclosed |
| US-7939546-B2 | Quinoline derivatives for modulating DNA methylation | SUPERGEN, INC. (US) | 2011-05-10 | — | — | US | disclosed |
| CN-101889008-A | Be used to regulate the quinoline of dna methylation | SUPERGEN INC | 2010-11-17 | — | — | CN | disclosed |
| CN-101535295-A | Quinoline derivatives for modulating DNA methylation | SUPERGEN INC (US) | 2009-09-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110256092-A1 | QUINOLINE DERIVATIVES FOR MODULATING DNA METHYLATION | DNMT1, DNMT3A, DNMT3L | HEXA 3990/4885HEXB 4152/4885DHFR 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.