SCHEMBL1885404

SCHEMBL1885404

O=C(OCCO)c1cc(O)c(O)c(O)c1

nearest known ligand 0.81

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 6/20 0.81
ESR1 P03372 2/20 0.66
AKR1C4 P17516 1/20 0.62
AKR1C3 P42330 1/20 0.62
AKR1C2 P52895 1/20 0.62
AKR1C1 Q04828 1/20 0.62
TYR P14679 3/20 0.60
L3MBTL1 Q9Y468 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL3515847 0.92 SERPINE1 (0.88) SERPINE1ESR1AKR1C4AKR1C3AKR1C2
SCHEMBL2791373 0.90 SERPINE1 (1.00) SERPINE1ESR1AKR1C4AKR1C3AKR1C2
SCHEMBL29022407 0.89 SERPINE1 (0.86) SERPINE1ESR1AKR1C4AKR1C3AKR1C2
SCHEMBL19642723 0.89 SERPINE1 (0.86) SERPINE1ESR1AKR1C4AKR1C3AKR1C2
SCHEMBL28384704 0.89 SERPINE1 (0.82) SERPINE1ESR1AKR1C4AKR1C3AKR1C2
SCHEMBL8382124 0.87 SERPINE1 (0.79) SERPINE1ESR1AKR1C4AKR1C3AKR1C2
Ethylene SCHEMBL16145015 0.86 SERPINE1 (0.92) SERPINE1ESR1AKR1C4AKR1C3AKR1C2
SCHEMBL13287172 0.86 SERPINE1 (0.92) SERPINE1ESR1AKR1C4AKR1C3AKR1C2
Ethylene SCHEMBL16144939 0.86 SERPINE1 (0.92) SERPINE1ESR1AKR1C4AKR1C3AKR1C2
Ethylene SCHEMBL16144936 0.86 SERPINE1 (0.92) SERPINE1ESR1AKR1C4AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559795-B2 Compositions, methods, kits, cartridges, and systems for sequencing reagents ILLUMINA, INC. (US) 2026-02-24 US claimed
US-20250138031-A1 IN VITRO MEASUREMENT OF THE LYSIS OF A FIBRIN CLOT DIAGNOSTICA STAGO (FR) 2025-05-01 US claimed
EP-4499870-A1 COMPOSITIONS AND METHODS FOR IMPROVING SEQUENCING SIGNALS Illumina, Inc. (US) 2025-02-05 EP claimed
CN-118834553-A Preparation method of flash rust inhibitor 大连连昇新材料有限公司 2024-10-25 CN claimed
EP-4359555-A1 COMPOSITIONS, METHODS, KITS, CARTRIDGES, AND SYSTEMS FOR SEQUENCING REAGENTS Illumina, Inc. (US) 2024-05-01 EP claimed
CN-117597453-A Compositions, methods, kits, cartridges, and systems for sequencing reagents 伊鲁米纳公司 2024-02-23 CN claimed
CN-117050625-A Water-based rust conversion coating for carbon nano tube and preparation method thereof 铁科金化检测中心有限公司 2023-11-14 CN claimed
US-20230357845-A1 COMPOSITIONS AND METHODS FOR IMPROVING SEQUENCING SIGNALS ILLUMINA, INC. 2023-11-09 US claimed
WO-2023186982-A1 COMPOSITIONS AND METHODS FOR IMPROVING SEQUENCING SIGNALS ILLUMINA, INC. (US) 2023-10-05 WO claimed
CN-113679039-B Polyethylene glycol gallate protein carrier synergist and preparation method and application thereof 浙江大学 2023-05-09 CN claimed
CN-111617035-A Application of micelle formed by polyethylene glycol derivative in paclitaxel or derivative thereof 天津力博生物科技有限公司 2020-09-04 CN claimed
CN-111423576-A Polyethylene glycol derivative and preparation method and application thereof 天津力博生物科技有限公司 2020-07-17 CN claimed
CN-106074589-A Comprise the compositions of S S-adenosylmethionine and epicatechol gallate 甲基化物科学国际有限公司 2016-11-09 CN claimed
CN-100432046-C Activator for endogenetic pathway of coagulation and their use for exploring anomalies of coagulation STAGO DIAGNOSTICA (FR) 2008-11-12 CN claimed
US-7208266-B2 Endogenous coagulation activator compounds —use in exploring endogenous coagulation SOCIETE DIAGNOSTICA-STAGO (FR) 2007-04-24 US claimed
EP-1512323-B1 Microbicidal composition based on formaldehyde donor compounds and antioxidants AIR LIQUIDE SANTE INT (FR) 2007-02-21 EP claimed
US-20050054642-A1 Microbicidal composition based on formaldehyde donor compounds and antioxidants SCHULKE & MAYR GMBH (DE) 2005-03-10 US claimed
EP-1512323-A1 Microbicidal composition based on formaldehyde donor compounds and antioxidants Air Liquide Santé (International) (FR) 2005-03-09 EP claimed
CN-1460098-A Activator for endogenetic pathway of coagulation and their use for exploring anomalies of coagulation STAGO DIAGNOSTICA (FR) 2003-12-03 CN claimed
US-20030157582-A1 Endogenous coagulation activator compounds - use in exploring endogenous coagulation SOCIETE DIAGNOSTICA-STAGO (FR) 2003-08-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157582-A1 Endogenous coagulation activator compounds - use in exploring endogenous coagulation TFPI, F2, F8 SERPINE1 20/4885ESR1 1071/4885AKR1C4 3564/4885
US-12559795-B2 Compositions, methods, kits, cartridges, and systems for sequencing reagents RNGTT, PHAX, RNMT SERPINE1 2276/4885ESR1 3814/4885AKR1C4 2770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.