Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901029 | 0.86 | MAPK1 (0.42) | MAPK1ALDH1A1THRB | |
| SCHEMBL18854317 | 0.86 | ALDH1A1 (0.35) | MAPK1ALDH1A1THRB | |
| SCHEMBL18854311 | 0.85 | MAPK1 (0.33) | MAPK1ALDH1A1THRB | |
| SCHEMBL24453808 | 0.84 | LMNA (0.41) | MAPK1ALDH1A1THRBMMP9MMP12 | |
| SCHEMBL16392993 | 0.81 | MAPK1 (0.33) | MAPK1ALDH1A1THRB | |
| SCHEMBL18854312 | 0.80 | MAPK1 (0.32) | MAPK1ALDH1A1THRB | |
| SCHEMBL18854315 | 0.79 | NEU3 (0.32) | MAPK1 | |
| SCHEMBL24454404 | 0.78 | MAPK1 (0.39) | MAPK1ALDH1A1THRBMMP9MMP12 | |
| SCHEMBL23603141 | 0.78 | MAPK1 (0.52) | MAPK1ALDH1A1THRB | |
| SCHEMBL21077729 | 0.78 | MAPK1 (0.52) | MAPK1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137801-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-05-18 | — | — | US | disclosed |