Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150321 | 0.84 | LMNA (0.40) | MAPK1SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL24996774 | 0.81 | MAPK1 (0.32) | MAPK1LMNAKMT2APOLBALDH1A1 | |
| SCHEMBL24996778 | 0.81 | MAPK1 (0.32) | MAPK1LMNAKMT2APOLBALDH1A1 | |
| SCHEMBL18854302 | 0.81 | MAPK1 (0.33) | MAPK1ALDH1A1THRB | |
| SCHEMBL12280200 | 0.77 | MAPK1 (0.46) | MAPK1LMNAKMT2AALDH1A1THRB | |
| SCHEMBL7155174 | 0.75 | LGALS3 (0.44) | MAPK1ALDH1A1THRB | |
| SCHEMBL7154489 | 0.75 | LGALS3 (0.44) | MAPK1ALDH1A1THRB | |
| SCHEMBL10819655 | 0.74 | SSTR3 (0.35) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL16392999 | 0.74 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1THRB | |
| SCHEMBL19546219 | 0.73 | FGF1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015006740-A2 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-01-15 | — | — | WO | disclosed |