Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19143350 | 0.82 | — | — | |
| SCHEMBL2504628 | 0.74 | DNM1 (0.43) | ACE2FDPSCA1ALDH1A1TSHR | |
| SCHEMBL1783357 | 0.72 | ACE2 (0.47) | ACE2FDPSCA1 | |
| SCHEMBL11688625 | 0.72 | ACE2 (0.62) | ACE2CA1 | |
| SCHEMBL16270614 | 0.72 | — | — | |
| SCHEMBL11775527 | 0.71 | ACE2 (0.46) | ACE2FDPSCA1ALDH1A1TSHR | |
| SCHEMBL11776511 | 0.71 | ACE2 (0.46) | ACE2FDPSCA1 | |
| SCHEMBL1658455 | 0.70 | ACE2 (0.39) | ACE2FDPSALDH1A1TSHRDNM1 | |
| SCHEMBL235264 | 0.70 | DNM1 (0.36) | ACE2FDPSALDH1A1TSHRDNM1 | |
| SCHEMBL873768 | 0.70 | ACE2 (0.39) | ACE2FDPSCA1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137437-A1 | SYNTHESIS OF HALICHONDRIN ANALOGS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137437-A1 | SYNTHESIS OF HALICHONDRIN ANALOGS AND USES THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, KIF5C, KIF23 | ACE2 3956/4885FDPS 1217/4885CA1 2141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.