KIF5C — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL3333345	0.58	1/20
SCHEMBL3329830	0.57	1/20
SCHEMBL11939079	0.55	1/20
SCHEMBL27775392	0.55	1/20
SCHEMBL3329866	0.54	1/20
SCHEMBL27796460	0.54	1/20
SCHEMBL301188	0.54	1/20
SCHEMBL3336116	0.54	1/20
SCHEMBL301157	0.51	1/20
SCHEMBL3333434	0.51	1/20
SCHEMBL3334412	0.50	1/20
SCHEMBL3334609	0.50	1/20
SCHEMBL296230	0.49	1/20
SCHEMBL27775753	0.47	1/20
SCHEMBL12288088	0.44	1/20
SCHEMBL300839	0.42	1/20
SCHEMBL22560009	0.42	1/20
SCHEMBL300818	0.42	1/20

Clinical trials — most relevant to KIF5C by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study	PHASE3	COMPLETED
Biologic Correlative Taxotere/AC	PHASE2	COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies	PHASE1	COMPLETED
Transcutaneous Functional Magnetic Muscle Stimulation in Critically Ill	nan	UNKNOWN
Spastic Paraplegia - Centers of Excellence Research Network	nan	RECRUITING
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome	nan	RECRUITING
Peripheral Neurofilament Levels and Amyotrophic Lateral Sclerosis	nan	COMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others	nan	RECRUITING
CoMPaSS-NMD - Computational Models for New Patients Stratification Strategies of HNMD	nan	ENROLLING_BY_INVITATION
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
Diagnostic of Chemotherapy Induced Neuropathy in Children	nan	COMPLETED
Evaluating the Relationship of Morphine Consumption and Pain-related Molecules in Hepatic Surgical Patients	nan	COMPLETED
Biomarker Research in Inherited Movement Disorders	nan	RECRUITING
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy	nan	COMPLETED
Clinical Importance of Carrier Status of Recessive Gene Mutations in Myopathy (CICS)	nan	UNKNOWN
Autologous Stem/Stromal Cells in Neurological Disorders and Disease	nan	UNKNOWN
Pediatric Evaluation and Registry for Liver Cholestasis in Canada	nan	RECRUITING
Mapping of End Stage Renal Disease Genetic Susceptibility in African Americans by Admixture Linkage Disequilibrium	nan	COMPLETED
Brain Involvement in Dystrophinopathies Part 2	nan	COMPLETED
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases	nan	COMPLETED
Biomarkers and Validation of Selected Outcome Measures (CMTBiomarker)	nan	COMPLETED
Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS)	nan	COMPLETED
White Matter Integrity According to BDNF Genotype After Stroke	nan	COMPLETED
Anthropogenetic Variability in the Group of Individuals With Febrile Seizures	nan	COMPLETED
Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development	nan	COMPLETED
Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases	nan	COMPLETED
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)	nan	RECRUITING
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies.	nan	RECRUITING
Mapping Disease Pathways for Biliary Atresia	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a KIF5C binder may also engage these)

Protein	Name	Similarity
P28738	—	1.000	P28738 →
P56536	—	1.000	P56536 →
P21613	—	1.000	P21613 →
KIF5B	Kinesin-1 heavy chain	1.000	landscape →
P35978	—	1.000	P35978 →
Q2PQA9	—	1.000	Q2PQA9 →
P17210	—	1.000	P17210 →
P34540	—	1.000	P34540 →
Q91785	—	1.000	Q91785 →
Q61768	—	1.000	Q61768 →
A8WVU9	—	1.000	A8WVU9 →
O43093	—	1.000	O43093 →
Q7Z4S6	—	1.000	Q7Z4S6 →
Q5R9K7	—	1.000	Q5R9K7 →
Q9GYZ0	—	1.000	Q9GYZ0 →
Q6QLM7	—	1.000	Q6QLM7 →
Q86Z98	—	1.000	Q86Z98 →
KIF5A	Kinesin heavy chain isoform 5A	0.999	landscape →
KIF15	Kinesin-like protein KIF15	0.999	landscape →
Q86ZC1	—	0.999	Q86ZC1 →
Q498L9	—	0.999	Q498L9 →
Q9QXL2	—	0.999	Q9QXL2 →
P46863	—	0.999	P46863 →
P92199	—	0.999	P92199 →
P46867	—	0.999	P46867 →
Q61771	—	0.999	Q61771 →
P46875	—	0.999	P46875 →
O35066	—	0.999	O35066 →
O14782	—	0.998	O14782 →
Q9H1H9	—	0.998	Q9H1H9 →