Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 7/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1885606 | 1.00 | AKR1B10 (0.52) | AKR1B10AKR1B1ALOX5APPKDM4E | |
| SCHEMBL1879383 | 0.92 | ALOX5 (0.60) | AKR1B10AKR1B1ALOX5APPKDM4E | |
| SCHEMBL1879385 | 0.92 | ALOX5 (0.60) | AKR1B10AKR1B1ALOX5APPKDM4E | |
| SCHEMBL1880415 | 0.90 | ABCG2 (0.57) | AKR1B10AKR1B1ALOX5APPKDM4E | |
| SCHEMBL1880416 | 0.90 | ABCG2 (0.57) | AKR1B10AKR1B1ALOX5APPKDM4E | |
| SCHEMBL1883743 | 0.87 | MAOB (0.54) | AKR1B10AKR1B1ALOX5ALDH1A1 | |
| SCHEMBL1883744 | 0.87 | MAOB (0.54) | AKR1B10AKR1B1ALOX5ALDH1A1 | |
| SCHEMBL29069534 | 0.85 | ABCG2 (0.54) | AKR1B10AKR1B1APPKDM4EALDH1A1 | |
| SCHEMBL9869579 | 0.84 | KDM4E (0.58) | AKR1B10AKR1B1ALOX5APPKDM4E | |
| SCHEMBL1879576 | 0.82 | ABCG2 (0.59) | AKR1B10AKR1B1ALOX5APPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666440-B1 | METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-7939674-B2 | Process for producing an aromatic unsaturated compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-10 | — | — | US | disclosed |
| US-7700642-B2 | Process for producing an aromatic unsaturated compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20090111999-A1 | PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20080221337-A1 | Process for Producing an Aromatic Unsaturated Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-09-11 | — | — | US | disclosed |
| EP-1666440-A1 | METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221337-A1 | Process for Producing an Aromatic Unsaturated Compound | AHR, AR, ARSA | AKR1B10 74/4885AKR1B1 44/4885ALOX5 32/4885 |
| US-20090111999-A1 | PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND | AHR, AR, ARSA | AKR1B10 74/4885AKR1B1 44/4885ALOX5 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.