SCHEMBL9869579

SCHEMBL9869579

CCCCOC(=O)/C=C/c1cccc(OC)c1O

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.58
ALDH1A1 P00352 2/20 0.58
HPGD P15428 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
BACE1 P56817 1/20 0.54
AKR1B10 O60218 5/20 0.53
AKR1B1 P15121 5/20 0.53
ALOX5 P09917 4/20 0.52
APP P05067 2/20 0.51
MAPT P10636 1/20 0.51
TXNRD1 Q16881 1/20 0.49
TXNRD3 Q86VQ6 1/20 0.49
TXNRD2 Q9NNW7 1/20 0.49
BCHE P06276 1/20 0.49
TLR2 O60603 1/20 0.49
ERN1 O75460 1/20 0.49
TLR1 Q15399 1/20 0.49
TLR6 Q9Y2C9 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1614877 0.88 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2AKR1B10
SCHEMBL19244312 0.88 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2AKR1B10
SCHEMBL7103115 0.88 KDM4E (0.59) KDM4EALDH1A1HPGDSMN1; SMN2BACE1
SCHEMBL5177689 0.85 KDM4E (0.73) KDM4EALDH1A1HPGDSMN1; SMN2AKR1B10
SCHEMBL466048 0.84 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2AKR1B10
SCHEMBL8872479 0.84 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2AKR1B10
SCHEMBL4421062 0.84 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2AKR1B10
SCHEMBL4629237 0.84 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2AKR1B10
SCHEMBL8872224 0.84 KDM4E (0.71) KDM4EALDH1A1HPGDSMN1; SMN2AKR1B10
SCHEMBL1885609 0.84 AKR1B10 (0.52) KDM4EALDH1A1HPGDSMN1; SMN2AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5024923-A Sulfur-containing metal complex FUJI PHOTO FILM CO., LTD. (JP) 1991-06-18 US disclosed
US-4913846-A Infrared absorbing composition FUJI PHOTO FILM CO., LTD. (JP) 1990-04-03 US disclosed