Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.53 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.44 |
| ▸ | HRH2 | P25021 | 4/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653523 | 0.86 | SLC6A5 (0.69) | SLC15A2SLC6A5CPB2EPHX2HRH3 | |
| SCHEMBL18857761 | 0.86 | SLC15A2 (0.58) | SLC15A2SLC6A5CPB2EPHX2HRH3 | |
| SCHEMBL7887542 | 0.86 | SLC6A5 (0.69) | SLC15A2SLC6A5CPB2EPHX2HRH3 | |
| SCHEMBL7257727 | 0.85 | SLC15A2 (0.69) | SLC15A2SLC6A5CPB2EPHX2HRH3 | |
| SCHEMBL26126281 | 0.81 | SLC15A2 (0.67) | SLC15A2SLC6A5CPB2EPHX2HRH3 | |
| SCHEMBL21631681 | 0.81 | SLC15A2 (0.67) | SLC15A2SLC6A5CPB2EPHX2HRH3 | |
| SCHEMBL541262 | 0.81 | SLC15A2 (0.67) | SLC15A2SLC6A5CPB2EPHX2HRH3 | |
| Carnosine SCHEMBL22191128 | 0.80 | SLC15A2 (0.69) | SLC15A2SLC6A5CPB2EPHX2HRH3 | |
| SCHEMBL19051460 | 0.78 | SLC15A2 (0.54) | SLC15A2SLC6A5CPB2EPHX2ITGB2 | |
| SCHEMBL16819891 | 0.77 | SLC15A2 (0.53) | SLC15A2SLC6A5CPB2EPHX2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017083368-A9 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | PFIZER INC. (US) | 2018-04-12 | — | — | WO | disclosed |
| WO-2017083368-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | PFIZER INC. (US) | 2017-05-18 | — | — | WO | disclosed |