Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | FSHR | P23945 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | LHCGR | P22888 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 5/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.30 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27017059 | 0.99 | MGMT (0.45) | MGMTMMP2MMP9MMP8MMP13 | |
| SCHEMBL18858999 | 0.83 | OPRM1 (0.43) | MGMTMMP2MMP9MMP8MMP13 | |
| SCHEMBL26448941 | 0.81 | MMP2 (0.41) | MGMTMMP2MMP9MMP8MMP13 | |
| SCHEMBL20046973 | 0.81 | MMP2 (0.47) | MGMTMMP2MMP9MMP8MMP13 | |
| SCHEMBL24569987 | 0.80 | MGMT (0.44) | MGMTMMP2MMP9MMP8MMP13 | |
| SCHEMBL15932535 | 0.79 | MMP2 (0.46) | MGMTMMP2MMP9MMP8MMP13 | |
| SCHEMBL20047063 | 0.79 | MGMT (0.43) | MGMTMMP2MMP9MMP8MMP13 | |
| SCHEMBL15281111 | 0.79 | CHRNA7 (0.38) | NCF1DPP4CHRNA7MAPK14DRD2 | |
| SCHEMBL17586038 | 0.79 | CHRNA7 (0.38) | NCF1DPP4CHRNA7MAPK14DRD2 | |
| SCHEMBL18850692 | 0.79 | CHRNA7 (0.38) | NCF1DPP4CHRNA7MAPK14DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137389-A1 | LINKER MOLECULE FOR MULTIPLEX RECOGNITION BY ATOMIC FORCE MICROSCOPY (AFM) | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137389-A1 | LINKER MOLECULE FOR MULTIPLEX RECOGNITION BY ATOMIC FORCE MICROSCOPY (AFM) | EPCAM, ILK, DYNLL2 | MGMT 3328/4885MMP2 1984/4885MMP9 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.