SCHEMBL18862054

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CNCN1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	GHSR	Q92847	10/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18862045	1.00	GHSR (0.58)	GHSR
SCHEMBL18862460	0.92	ERAP2 (0.54)	—
SCHEMBL18857368	0.92	GHSR (0.66)	GHSR
SCHEMBL18862071	0.92	ERAP2 (0.54)	—
SCHEMBL18862051	0.92	ERAP2 (0.54)	—
SCHEMBL18862334	0.84	GHSR (0.57)	GHSR
SCHEMBL18862458	0.84	GHSR (0.70)	GHSR
SCHEMBL18862050	0.83	IL1RN (0.51)	—
SCHEMBL30051718	0.82	ERAP2 (0.64)	—
SCHEMBL30169818	0.82	ERAP2 (0.64)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20170137801-A1	TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA	2017-05-18	—	—	US	disclosed