Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.59 |
| ▸ | HRH1 | P35367 | 2/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18862259 | 0.98 | REN (0.57) | RENHRH1ERAP2ERAP1LNPEP | |
| SCHEMBL18862365 | 0.92 | REN (0.67) | RENHRH1ERAP2ERAP1LNPEP | |
| SCHEMBL18862362 | 0.91 | REN (0.63) | RENHRH1CTSD | |
| SCHEMBL18862235 | 0.91 | REN (0.65) | RENHRH1ERAP2ERAP1LNPEP | |
| SCHEMBL22722179 | 0.91 | REN (0.65) | RENHRH1ERAP2ERAP1LNPEP | |
| SCHEMBL18857602 | 0.90 | REN (0.64) | RENHRH1ERAP2ERAP1LNPEP | |
| SCHEMBL18862444 | 0.82 | REN (0.55) | RENHRH1ERAP2ERAP1LNPEP | |
| SCHEMBL18862059 | 0.82 | REN (0.54) | RENHRH1ERAP2ERAP1LNPEP | |
| SCHEMBL18862332 | 0.81 | REN (0.69) | RENHRH1ERAP2ERAP1LNPEP | |
| SCHEMBL18862086 | 0.80 | REN (0.51) | RENHRH1ERAP2ERAP1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137801-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-05-18 | — | — | US | disclosed |