Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.63 |
| ▸ | HRH1 | P35367 | 2/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18862249 | 0.91 | REN (0.59) | RENHRH1CTSD | |
| SCHEMBL18862332 | 0.91 | REN (0.69) | RENHRH1CTSD | |
| SCHEMBL18862259 | 0.90 | REN (0.57) | RENHRH1 | |
| SCHEMBL18854266 | 0.86 | REN (0.63) | RENHRH1 | |
| SCHEMBL18857765 | 0.83 | GHSR (0.51) | — | |
| SCHEMBL18862365 | 0.83 | REN (0.67) | RENHRH1 | |
| SCHEMBL22722179 | 0.81 | REN (0.65) | RENHRH1 | |
| SCHEMBL18862235 | 0.81 | REN (0.65) | RENHRH1 | |
| SCHEMBL20868190 | 0.81 | REN (0.60) | RENHRH1 | |
| SCHEMBL18857369 | 0.81 | REN (0.57) | RENHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137801-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-05-18 | — | — | US | disclosed |