Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SELL | P14151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18862777 | 0.93 | POLB (0.50) | TTRDHODHPOLBHCAR2CA12 | |
| SCHEMBL8361 | 0.85 | TTR (0.56) | TTRPOLBHCAR2CA12CA1 | |
| SCHEMBL23501889 | 0.85 | TTR (0.56) | TTRPOLBHCAR2CA12CA1 | |
| SCHEMBL475757 | 0.85 | TTR (0.56) | TTRPOLBHCAR2CA12CA1 | |
| SCHEMBL145349 | 0.84 | DHODH (0.58) | TTRDHODHCA12CA1CA2 | |
| SCHEMBL18875268 | 0.82 | DHODH (0.36) | TTRDHODHPOLBHCAR2TPMT | |
| Hydrochloric Acid SCHEMBL11153457 | 0.82 | TTR (0.54) | TTRPOLBHCAR2CA12CA1 | |
| SCHEMBL27896747 | 0.82 | TTR (0.54) | TTRPOLBHCAR2CA12CA1 | |
| SCHEMBL30367425 | 0.82 | RXRA (0.59) | CA12CA1CA2CA9CA14 | |
| SCHEMBL12203147 | 0.82 | DHODH (0.57) | TTRDHODHCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10069082-B2 | Organic electroluminescent compounds and organic optoelectronic devices comprising the same | Shanghai Tianma AM-OLED Co., Ltd. (CN) | 2018-09-04 | — | — | US | disclosed |
| US-20170148996-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC OPTOELECTRONIC DEVICES COMPRISING THE SAME | WUHAN TIANMA MICROELECTRONICS CO., LTD.SHANGHAI BRANCH (CN) | 2017-05-25 | — | — | US | disclosed |
| US-20170148996-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC OPTOELECTRONIC DEVICES COMPRISING THE SAME | WUHAN TIANMA MICROELECTRONICS CO., LTD.SHANGHAI BRANCH (CN) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10069082-B2 | Organic electroluminescent compounds and organic optoelectronic devices comprising the same | OR10J3, PPOX, OR51E2 | TTR 425/4885DHODH 905/4885POLB 1048/4885 |
| US-20170148996-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC OPTOELECTRONIC DEVICES COMPRISING THE SAME | OR10J3, PPOX, OR51E2 | TTR 425/4885DHODH 905/4885POLB 1048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.