Sugi Predict

Sugi Predict / Compounds / SCHEMBL8361

SCHEMBL8361

SCHEMBL8361

O=C(O)c1cc(Br)cc(Br)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 2/20 0.56
▸ POLB P06746 2/20 0.56
▸ HCAR2 Q8TDS4 1/20 0.56
▸ CA12 O43570 3/20 0.50
▸ CA1 P00915 3/20 0.50
▸ CA2 P00918 3/20 0.50
▸ CA7 P43166 3/20 0.50
▸ CA9 Q16790 3/20 0.50
▸ CA14 Q9ULX7 3/20 0.50
▸ TPMT P51580 4/20 0.48
▸ TP53 P04637 2/20 0.48
▸ CA3 P07451 2/20 0.48
▸ CA4 P22748 2/20 0.48
▸ CA6 P23280 2/20 0.48
▸ CA5A P35218 2/20 0.48
▸ CA5B Q9Y2D0 2/20 0.48
▸ KDM4E B2RXH2 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11153457 0.97 TTR (0.54) TTRPOLBHCAR2CA12CA1
SCHEMBL23501889 0.94 TTR (0.56) TTRPOLBHCAR2CA12CA1
SCHEMBL475757 0.94 TTR (0.56) TTRPOLBHCAR2CA12CA1
SCHEMBL27896747 0.92 TTR (0.54) TTRPOLBHCAR2CA12CA1
Ethylene SCHEMBL28706399 0.89 TTR (0.52) TTRPOLBHCAR2CA12CA1
SCHEMBL18862777 0.87 POLB (0.50) TTRPOLBHCAR2CA12CA1
SCHEMBL29422455 0.85 CA12 (0.68) TTRPOLBHCAR2CA12CA1
SCHEMBL18862820 0.85 TTR (0.48) TTRPOLBHCAR2CA12CA1
SCHEMBL200289 0.85 CA12 (0.68) TTRPOLBHCAR2CA12CA1
SCHEMBL1028516 0.83 KDM4E (0.47) TTRPOLBHCAR2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 704 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 — — EP claimed
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 — — US claimed
EP-4501896-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND Kao Corporation (JP) 2025-02-05 — — EP claimed
CN-118973990-A Process for producing cyclic diketone compound 花王株式会社 2024-11-15 — — CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 — — WO claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 — — CN claimed
CN-117603604-B Preparation method of printing gloss oil with amino-terminated hyperbranched self-assembled polyamide as main component 江苏众立生包装科技有限公司 2024-05-24 — — CN claimed
CN-117753230-A preparation method of borneol ester-containing conjugated microporous polymer/MXene chiral composite membrane 齐齐哈尔大学 2024-03-26 — — CN claimed
CN-117603604-A Preparation method of printing gloss oil with amino-terminated hyperbranched self-assembled polyamide as main component 江苏众立生包装科技有限公司 2024-02-27 — — CN claimed
CN-117263908-A Preparation of 1-pyridylpyrazole amide compound and intermediate thereof 湖南化工研究院有限公司 2023-12-22 — — CN claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 — — US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 — — US claimed
EP-1381672-A4 BIOSYNTHESIS OF POLYKETIDE SYNTHASE SUBSTRATES TRUSTEES OF BOARD OF (US) 2006-01-25 — — EP claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 — — US claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 — — EP claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 — — US claimed
EP-1381672-A1 BIOSYNTHESIS OF POLYKETIDE SYNTHASE SUBSTRATES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2004-01-21 — — EP claimed
US-20020192767-A1 Biosynthesis of polyketide synthase substrates NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-12-19 — — US claimed
WO-2002068613-A1 BIOSYNTHESIS OF POLYKETIDE SYNTHASE SUBSTRATES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2002-09-06 — — WO claimed
US-20020045220-A1 Biosynthesis of polyketide synthase substrates LELAND STANFORD JUNIOR UNIVERSITY, THE 2002-04-18 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND HSD17B7, HSD17B12, BCKDK TTR 4769/4885POLB 743/4885HCAR2 3107/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 TTR 2094/4885POLB 1788/4885HCAR2 3310/4885
US-20020045220-A1 Biosynthesis of polyketide synthase substrates COASY, DCXR, KYAT3 TTR 4015/4885POLB 271/4885HCAR2 2246/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 TTR 22/4885POLB 1132/4885HCAR2 2828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.