SCHEMBL1886591

SCHEMBL1886591

COc1ccc(CCN)cc1N/N=C(/C(C)=O)C(=O)Nc1ccccc1OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.51
ALDH1A1 P00352 3/20 0.51
MAPK1 P28482 2/20 0.51
TDP1 Q9NUW8 2/20 0.48
POLB P06746 1/20 0.48
CASP6 P55212 1/20 0.48
TSHR P16473 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
NFKB1 P19838 1/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 2/20 0.42
ATM Q13315 1/20 0.42
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
APEX1 P27695 1/20 0.41
RAB9A P51151 2/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1886597 1.00 MAPT (0.51) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL14435616 0.81 TDP1 (0.51) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL1880156 0.81 ALDH1A1 (0.48) MAPTALDH1A1LMNAKMT2AMEN1
SCHEMBL1880162 0.81 ALDH1A1 (0.48) MAPTALDH1A1LMNAKMT2AMEN1
SCHEMBL12638062 0.81 ALDH1A1 (0.48) MAPTALDH1A1LMNAKMT2AMEN1
SCHEMBL12299491 0.80 ALDH1A1 (0.58) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL14531025 0.78 ALDH1A1 (0.53) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL12998571 0.77 ALDH1A1 (0.65) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL12299489 0.76 ALDH1A1 (0.58) MAPTALDH1A1MAPK1TDP1POLB
SCHEMBL765365 0.76 MAPT (0.55) MAPTALDH1A1MAPK1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110207860-A1 Inkjet Ink Compositions Comprising Polymeric Dispersants Having Attached Chromophore Groups CABOT CORPORATION (US) 2011-08-25 US disclosed
US-20110207860-A1 Inkjet Ink Compositions Comprising Polymeric Dispersants Having Attached Chromophore Groups CABOT CORPORATION (US) 2011-08-25 US disclosed
US-7947761-B2 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION (US) 2011-05-24 US disclosed
US-7947761-B2 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION (US) 2011-05-24 US disclosed
US-7947761-B2 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION (US) 2011-05-24 US disclosed
US-20070179214-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179214-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179214-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179213-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179213-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179215-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179215-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179215-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed
US-20070179213-A1 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION 2007-08-02 US disclosed