Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | KYNU | Q16719 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13666886 | 0.94 | ITGAL (0.65) | ITGALS1PR1DRD3SLC6A3S1PR4 | |
| SCHEMBL13668215 | 0.86 | ITGAL (0.51) | ITGALS1PR1DRD3SLC6A3PYGL | |
| SCHEMBL14613755 | 0.80 | ITGAL (0.45) | ITGALS1PR1DRD3SLC6A3S1PR4 | |
| SCHEMBL18885625 | 0.80 | ITGAL (0.60) | ITGALS1PR1PYGLKYNUITGB1 | |
| SCHEMBL14613923 | 0.79 | ITGAL (0.67) | ITGALPYGLKYNUITGB1ITGA4 | |
| SCHEMBL18867651 | 0.78 | ITGAL (0.47) | ITGALDRD3SLC6A3KYNUEPHX2 | |
| SCHEMBL16307471 | 0.77 | ITGAL (0.57) | ITGALS1PR1ITGB1ITGA4ITGA2 | |
| SCHEMBL18881151 | 0.76 | ITGAL (0.56) | ITGALS1PR1PYGLITGB1ITGA4 | |
| SCHEMBL19157703 | 0.76 | ITGAL (0.56) | ITGALITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL18362373 | 0.76 | ITGAL (0.55) | ITGALDRD3SLC6A3HTR2BKYNU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | SARcode Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |