Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162350 | 0.79 | — | — | |
| SCHEMBL1882670 | 0.79 | MAPK14 (0.39) | IDO1ABCG2ACHE | |
| SCHEMBL1887676 | 0.79 | MAPK14 (0.39) | IDO1ABCG2L3MBTL1NR4A2ACHE | |
| SCHEMBL4151460 | 0.77 | PRKD3 (0.33) | — | |
| SCHEMBL1883929 | 0.77 | PIK3CA (0.42) | — | |
| SCHEMBL4718820 | 0.77 | — | — | |
| SCHEMBL1883294 | 0.77 | TOP1 (0.39) | ALDH1A1CCR1CCR8L3MBTL1NR4A2 | |
| SCHEMBL1892023 | 0.71 | F7 (0.38) | F10F7F3IDO1ACHE | |
| SCHEMBL252439 | 0.69 | L3MBTL1 (0.44) | ALDH1A1IDO1CCR1CCR8L3MBTL1 | |
| SCHEMBL4022147 | 0.69 | METAP1 (0.51) | ALDH1A1CCR1CCR8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| EP-1585746-B1 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA LTD (GB) | 2007-01-31 | — | — | EP | disclosed |
| US-20060069089-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2006-03-30 | — | — | US | disclosed |
| EP-1585746-A2 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | Syngenta Limited (GB) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004056824-A2 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069089-A1 | Fungicides | CBR3, TACR3, HCRTR1 | ALDH1A1 3663/4885F2 4425/4885F10 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.