Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928445 | 0.88 | PRKD3 (0.32) | PRKD3TGFBR1PRKD1PRKD2 | |
| SCHEMBL14086458 | 0.81 | PRKD3 (0.30) | PRKD3TGFBR1PRKD1PRKD2 | |
| SCHEMBL13906856 | 0.81 | PRKD3 (0.30) | PRKD3TGFBR1PRKD1PRKD2 | |
| SCHEMBL5223150 | 0.80 | — | — | |
| SCHEMBL13906853 | 0.78 | SMN1; SMN2 (0.37) | PRKD3TGFBR1PRKD1PRKD2ADORA2A | |
| SCHEMBL21170633 | 0.78 | PRKD3 (0.31) | PRKD3TGFBR1PRKD1PRKD2 | |
| SCHEMBL4870273 | 0.78 | PRKD3 (0.33) | PRKD3TGFBR1PRKD1PRKD2 | |
| SCHEMBL14086455 | 0.78 | SMN1; SMN2 (0.37) | ADORA2A | |
| SCHEMBL4164674 | 0.78 | MAPK14 (0.32) | PRKD3TGFBR1PRKD1PRKD2 | |
| SCHEMBL1886840 | 0.77 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903436-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES | UNIV PENNSYLVANIA (US) | 2019-07-17 | — | — | EP | disclosed |
| EP-2903436-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES | UNIV PENNSYLVANIA (US) | 2019-07-17 | — | — | EP | disclosed |
| EP-3219207-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES | The Trustees Of The University Of Pennsylvania (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-3219207-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES | The Trustees Of The University Of Pennsylvania (US) | 2017-09-20 | — | — | EP | disclosed |
| US-20170173016-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES | NIH - DEITR | 2017-06-22 | — | — | US | disclosed |
| US-20170173016-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES | NIH - DEITR | 2017-06-22 | — | — | US | disclosed |
| US-20170173016-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES | NIH - DEITR | 2017-06-22 | — | — | US | disclosed |
| US-9649317-B2 | Heterocyclic compounds and their use for the treatment of neurodegenerative tauopathies | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-05-16 | — | — | US | disclosed |
| US-9649317-B2 | Heterocyclic compounds and their use for the treatment of neurodegenerative tauopathies | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-05-16 | — | — | US | disclosed |
| US-9649317-B2 | Heterocyclic compounds and their use for the treatment of neurodegenerative tauopathies | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-05-16 | — | — | US | disclosed |
| US-20090069333-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-03-12 | — | — | US | disclosed |
| US-20090069333-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-03-12 | — | — | US | disclosed |
| US-20090069333-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-03-12 | — | — | US | disclosed |
| US-7410967-B2 | Pyridodiazines as plant fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-7410967-B2 | Pyridodiazines as plant fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-7410967-B2 | Pyridodiazines as plant fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| EP-1575948-B1 | PYRIDODIAZINES AS PLANT FUNGICIDES | SYNGENTA LTD (GB) | 2007-02-14 | — | — | EP | disclosed |
| US-20060205717-A1 | Pyridodiazines as plant fungicides | SYNGENTA CROP PROTECTION, INC. | 2006-09-14 | — | — | US | disclosed |
| EP-1575948-A1 | PYRIDODIAZINES AS PLANT FUNGICIDES | Syngenta Limited (GB) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056825-A1 | PYRIDODIAZINES AS PLANT FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173016-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES | MAPT, PRNP, PSEN2 | PRKD3 2587/4885TGFBR1 4549/4885PRKD1 3285/4885 |
| US-20090069333-A1 | FUNGICIDES | CYP4Z1, CYP4X1, PRXL2A | PRKD3 1341/4885TGFBR1 1606/4885PRKD1 1608/4885 |
| US-20060205717-A1 | Pyridodiazines as plant fungicides | CYP4Z1, CYP4X1, PNPO | PRKD3 2700/4885TGFBR1 459/4885PRKD1 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.