Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 6/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162294 | 0.79 | — | — | |
| SCHEMBL1887290 | 0.79 | MAPK14 (0.39) | TOP1SLC40A1PRMT5GRM4L3MBTL1 | |
| SCHEMBL4151460 | 0.77 | PRKD3 (0.33) | GRM4 | |
| SCHEMBL1886840 | 0.77 | ALDH1A1 (0.36) | CCR1CCR8L3MBTL1ALDH1A1NR4A2 | |
| SCHEMBL4715968 | 0.77 | CYP1A2 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1892023 | 0.71 | F7 (0.38) | — | |
| SCHEMBL7435562 | 0.69 | PRMT5 (0.46) | TOP1PRMT5CCR1CCR8L3MBTL1 | |
| SCHEMBL4022147 | 0.69 | METAP1 (0.51) | CCR1CCR8L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL9275208 | 0.68 | SLC40A1 (0.50) | SLC40A1GRM4CCR1CCR8L3MBTL1 | |
| SCHEMBL4928547 | 0.68 | NOS1 (0.40) | L3MBTL1ALDH1A1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| EP-1585746-B1 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA LTD (GB) | 2007-01-31 | — | — | EP | disclosed |
| EP-1585746-B1 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA LTD (GB) | 2007-01-31 | — | — | EP | disclosed |
| US-20060069089-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2006-03-30 | — | — | US | disclosed |
| EP-1585746-A2 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | Syngenta Limited (GB) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004056824-A2 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069089-A1 | Fungicides | CBR3, TACR3, HCRTR1 | TOP1 1158/4885SLC40A1 3334/4885PRMT5 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.