SCHEMBL18868439

SCHEMBL18868439

c1ccc(-c2ccc(-c3cnc(-c4c5c(c(-c6ncc(-c7ccc(-c8ccccc8)cc7)o6)c6nsnc46)N=S=N5)o3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.53
▸ ALOX15 P16050 1/20 0.53
▸ CASP1 P29466 1/20 0.53
▸ RAB9A P51151 8/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ MEN1 O00255 2/20 0.47
▸ MITF O75030 1/20 0.47
▸ NPC1 O15118 7/20 0.43
▸ KDM4E B2RXH2 5/20 0.43
▸ ALDH1A1 P00352 5/20 0.43
▸ HPGD P15428 5/20 0.43
▸ HSD17B10 Q99714 4/20 0.43
▸ ATM Q13315 1/20 0.43
▸ GAA P10253 3/20 0.42
▸ SMN1; SMN2 Q16637 3/20 0.42
▸ CYP1A2 P05177 2/20 0.42
▸ CYP2C9 P11712 2/20 0.42
▸ CYP2C19 P33261 2/20 0.42
▸ CASP3 P42574 2/20 0.42
▸ SENP8 Q96LD8 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17173799 0.90 ALOX15 (0.53) TSHRALOX15CASP1RAB9AKMT2A
SCHEMBL18868438 0.89 TSHR (0.43) TSHRALOX15CASP1RAB9AKMT2A
SCHEMBL17173792 0.81 ALDH1A1 (0.37) TSHRALOX15CASP1RAB9AKMT2A
SCHEMBL18868441 0.80 NPC1 (0.49) TSHRALOX15RAB9AKMT2AMEN1
SCHEMBL17173798 0.79 ALOX15 (0.43) TSHRALOX15CASP1RAB9AKMT2A
SCHEMBL18868436 0.78 PDK2 (0.33) TSHRALOX15CASP1RAB9AKMT2A
SCHEMBL2684521 0.73 ALOX15 (0.96) TSHRALOX15CASP1RAB9AKMT2A
SCHEMBL77084 0.73 ALOX15 (0.96) TSHRALOX15CASP1RAB9AKMT2A
SCHEMBL1267325 0.73 ALOX15 (0.96) TSHRALOX15CASP1RAB9AKMT2A
SCHEMBL9238093 0.73 ALOX15 (0.96) TSHRALOX15CASP1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10804472-B2 Light-emitting element, light-emitting device, light source, authentication device, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2020-10-13 — — US disclosed
US-10431761-B2 Light-emitting element, light-emitting device, authentication device, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2019-10-01 — — US disclosed
US-20170141337-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC APPARATUS LUMITEK DISPLAY TECHNOLOGY LIMITED (IE) 2017-05-18 — — US disclosed
US-20170141337-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC APPARATUS LUMITEK DISPLAY TECHNOLOGY LIMITED (IE) 2017-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170141337-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC APPARATUS CYBA, AAAS, UGT1A8 TSHR 4571/4885ALOX15 1513/4885CASP1 1275/4885
US-10431761-B2 Light-emitting element, light-emitting device, authentication device, and electronic apparatus CYBA, AAAS, UGT1A8 TSHR 4571/4885ALOX15 1513/4885CASP1 1275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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