SCHEMBL18868441

SCHEMBL18868441

c1ccc(-c2ccc(-c3nnc(-c4c5c(c(-c6nnc(-c7ccc(-c8ccccc8)cc7)o6)c6nsnc46)N=S=N5)o3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 14/20 0.49
▸ RAB9A P51151 14/20 0.49
▸ SMN1; SMN2 Q16637 8/20 0.49
▸ HPGD P15428 6/20 0.47
▸ ALDH1A1 P00352 5/20 0.47
▸ KDM4E B2RXH2 4/20 0.47
▸ HSD17B10 Q99714 2/20 0.47
▸ GLA P06280 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ ALOX15 P16050 1/20 0.47
▸ NFKB1 P19838 2/20 0.45
▸ NFKB2 Q00653 2/20 0.45
▸ RELA Q04206 2/20 0.45
▸ POLB P06746 1/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ GAA P10253 1/20 0.43
▸ ATAD2 Q6PL18 1/20 0.42
▸ CA1 P00915 2/20 0.42
▸ CA2 P00918 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18868444 0.88 NPC1 (0.39) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL17173799 0.80 ALOX15 (0.53) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL18868439 0.80 TSHR (0.53) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL17173792 0.78 ALDH1A1 (0.37) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL18868440 0.76 PDK2 (0.35) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL522555 0.74 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL22858502 0.74 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL74999 0.74 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL46424 0.74 NPC1 (0.90) NPC1RAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL17173791 0.74 RAB9A (0.38) NPC1RAB9AHPGDALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10804472-B2 Light-emitting element, light-emitting device, light source, authentication device, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2020-10-13 — — US disclosed
US-10431761-B2 Light-emitting element, light-emitting device, authentication device, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2019-10-01 — — US disclosed
US-20170141337-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC APPARATUS LUMITEK DISPLAY TECHNOLOGY LIMITED (IE) 2017-05-18 — — US disclosed
US-20170141337-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC APPARATUS LUMITEK DISPLAY TECHNOLOGY LIMITED (IE) 2017-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170141337-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC APPARATUS CYBA, AAAS, UGT1A8 NPC1 1668/4885RAB9A 2470/4885SMN1; SMN2 2623/4885
US-10431761-B2 Light-emitting element, light-emitting device, authentication device, and electronic apparatus CYBA, AAAS, UGT1A8 NPC1 1668/4885RAB9A 2470/4885SMN1; SMN2 2623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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