Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23660937 | 0.81 | KMO (0.41) | KMOPRSS1PRSS2PRSS3DHODH | |
| SCHEMBL20470769 | 0.80 | AKT1 (0.46) | MAPTTDP1AKT1LMNA | |
| SCHEMBL18868783 | 0.80 | AKT1 (0.46) | MAPTTDP1AKT1LMNA | |
| SCHEMBL21574123 | 0.73 | RARB (0.37) | MGLLRXRARXRBMAPTLMNA | |
| SCHEMBL23430339 | 0.73 | DHODH (0.39) | KMOPRSS1PRSS2PRSS3DHODH | |
| SCHEMBL23750310 | 0.72 | KMO (0.49) | KMOPRSS1PRSS2PRSS3DHODH | |
| SCHEMBL13052186 | 0.69 | KMO (0.40) | KMOPRSS1PRSS2PRSS3DHODH | |
| SCHEMBL19801364 | 0.68 | HDAC8 (0.47) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL14471650 | 0.68 | KMO (0.54) | KMOPRSS1PRSS2PRSS3DHODH | |
| SCHEMBL2135450 | 0.67 | KMO (0.55) | KMOPRSS1PRSS2PRSS3DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230403927-A1 | AROMATIC COMPOUNDS | UDC IRELAND LTD (IE) | 2023-12-14 | — | — | US | disclosed |
| US-11800787-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2023-10-24 | — | — | US | disclosed |
| US-20170141329-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230403927-A1 | AROMATIC COMPOUNDS | TYR, CTCF, MITF | KMO 498/4885PRSS1 4055/4885PRSS2 3342/4885 |
| US-20170141329-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | KMO 2144/4885PRSS1 2820/4885PRSS2 1793/4885 |
| US-11800787-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | KMO 2144/4885PRSS1 2820/4885PRSS2 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.