Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.35 |
| ▸ | ITGAL | P20701 | 3/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18867998 | 0.82 | HDAC6 (0.39) | NPSR1HTTHDAC6CYP3A4CYP2C9 | |
| SCHEMBL18362337 | 0.78 | HDAC6 (0.46) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL13894120 | 0.74 | ITGB2 (0.55) | ITGB2ICAM1ITGAL | |
| SCHEMBL18867982 | 0.71 | ITGB2 (0.42) | ITGB2ICAM1ITGAL | |
| SCHEMBL22615579 | 0.65 | MTHFD2 (0.40) | CHRNA7 | |
| SCHEMBL22615401 | 0.65 | AURKA (0.39) | LMNAKMT2AHPGDALDH1A1 | |
| SCHEMBL23176589 | 0.65 | HDAC6 (0.42) | HTTHDAC6LMNAHPGDITGB2 | |
| SCHEMBL23979102 | 0.64 | ITGB2 (0.58) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL18867799 | 0.64 | ITGB2 (0.55) | CYP2C9ITGB2ICAM1ITGAL | |
| SCHEMBL20439976 | 0.64 | POLB (0.50) | HTTLMNARECQLCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | SARcode Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |