Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.80 |
| ▸ | POLB | P06746 | 3/20 | 0.80 |
| ▸ | HPGD | P15428 | 3/20 | 0.80 |
| ▸ | PKM | P14618 | 2/20 | 0.80 |
| ▸ | USP2 | O75604 | 2/20 | 0.80 |
| ▸ | BLM | P54132 | 2/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.71 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.70 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.55 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997551 | 0.84 | KDM4D (0.98) | MEN1KMT2APOLBHPGDPKM | |
| SCHEMBL5992705 | 0.83 | KDM4D (1.00) | MEN1KMT2APOLBHPGDPKM | |
| SCHEMBL13720219 | 0.74 | KDM4E (1.00) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL14119558 | 0.74 | KDM4E (0.71) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL5995022 | 0.73 | KDM4D (1.00) | MEN1KMT2APOLBHPGDUSP2 | |
| SCHEMBL9613308 | 0.71 | TDP1 (1.00) | MEN1KMT2APOLBHPGDPKM | |
| SCHEMBL13856682 | 0.70 | PTPN7 (1.00) | MEN1KMT2APOLBHPGDPKM | |
| SCHEMBL9613359 | 0.70 | PTPN7 (0.77) | MEN1KMT2APOLBHPGDUSP2 | |
| SCHEMBL9613368 | 0.70 | PTPN7 (1.00) | MEN1KMT2APOLBHPGDPKM | |
| SCHEMBL9613317 | 0.69 | KDM4D (0.82) | MEN1KMT2APOLBHPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9648880-B2 | Antifungal agents and uses thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2017-05-16 | — | — | US | disclosed |