Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 4/20 | 1.00 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 1.00 |
| ▸ | PTPN7 | P35236 | 8/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.76 |
| ▸ | HTT | P42858 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.76 |
| ▸ | CASP1 | P29466 | 2/20 | 0.76 |
| ▸ | BLM | P54132 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.76 |
| ▸ | APEX1 | P27695 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997551 | 0.99 | KDM4D (0.98) | KDM4DATG4BPTPN7ALDH1A1KMT2A | |
| SCHEMBL13856682 | 0.86 | PTPN7 (1.00) | KDM4DATG4BPTPN7ALDH1A1KMT2A | |
| SCHEMBL9613308 | 0.85 | TDP1 (1.00) | KDM4DATG4BPTPN7ALDH1A1KMT2A | |
| SCHEMBL18868635 | 0.83 | MEN1 (0.80) | KDM4DATG4BPTPN7ALDH1A1KMT2A | |
| SCHEMBL20866608 | 0.78 | ALDH1A1 (0.64) | KDM4DATG4BALDH1A1KMT2AKDM4E | |
| SCHEMBL5995022 | 0.77 | KDM4D (1.00) | KDM4DATG4BPTPN7ALDH1A1KMT2A | |
| SCHEMBL9613368 | 0.76 | PTPN7 (1.00) | KDM4DATG4BPTPN7ALDH1A1KMT2A | |
| SCHEMBL9613317 | 0.75 | KDM4D (0.82) | KDM4DATG4BPTPN7ALDH1A1KMT2A | |
| SCHEMBL20272250 | 0.75 | KDM4D (0.82) | KDM4DATG4BPTPN7ALDH1A1KMT2A | |
| SCHEMBL9613359 | 0.74 | PTPN7 (0.77) | KDM4DPTPN7ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |