SCHEMBL18869352

SCHEMBL18869352

C=CC(=O)Oc1ccc2cc(OC)ccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.55
AKR1C3 P42330 4/20 0.50
AKR1C2 P52895 4/20 0.50
CYP1A2 P05177 4/20 0.50
PTGS1 P23219 3/20 0.50
THRB P10828 2/20 0.50
CYP2A6 P11509 1/20 0.50
PTGS2 P35354 3/20 0.49
TSHR P16473 2/20 0.49
CDC42 P60953 1/20 0.49
RAC1 P63000 1/20 0.49
SLC22A6 Q4U2R8 1/20 0.49
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
NPC1 O15118 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAOA P21397 1/20 0.47
SLC6A2 P23975 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27421503 0.96 CYP1A2 (0.52) KDM4EAKR1C3AKR1C2CYP1A2PTGS1
SCHEMBL18869506 0.93 KDM4E (0.49) KDM4EAKR1C3AKR1C2CYP1A2PTGS1
SCHEMBL819722 0.90 THRB (0.53) KDM4ETHRBTSHRLMNAMAPT
SCHEMBL7186345 0.87 CES2 (0.52) KDM4ETHRBLMNANPC1RAB9A
SCHEMBL13538604 0.86 THRB (0.50) KDM4ETHRBTSHRLMNAMAPT
SCHEMBL12245560 0.86 THRB (0.50) KDM4ETHRBTSHRMAPTNPC1
SCHEMBL1061204 0.86 THRB (0.59) CYP1A2THRBLMNAMAPTSMN1; SMN2
SCHEMBL15302744 0.86 THRB (0.50) KDM4ETHRBTSHRLMNAMAPT
SCHEMBL18468607 0.83 RELA (0.58) KDM4ECYP1A2MEN1KMT2A
SCHEMBL19157824 0.83 ERN1 (0.46) KDM4EAKR1C3AKR1C2THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3924447-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2024-01-24 EP disclosed
EP-3755764-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2023-05-10 EP disclosed
EP-4001378-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2022-05-25 EP disclosed
EP-3985085-A2 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2022-04-20 EP disclosed
EP-3489329-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2022-01-12 EP disclosed
EP-3688118-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2021-05-19 EP disclosed
EP-3757192-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2020-12-30 EP disclosed
EP-3677659-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2020-07-08 EP disclosed
EP-2881383-B1 Mixing device and its use MERCK PATENT GMBH (DE) 2020-06-24 EP disclosed
EP-3353261-B1 METHOD OF CONTROLLING THE PRETILT ANGLE IN POLYMER STABILISED LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2020-05-27 EP disclosed
EP-3149109-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2019-10-16 EP disclosed
EP-2921545-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2019-08-21 EP disclosed
EP-3067406-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-04-24 EP disclosed
EP-2703472-B1 Liquid crystalline medium MERCK PATENT GMBH (DE) 2018-07-04 EP disclosed
EP-2985334-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-06-20 EP disclosed
EP-3083408-B1 FILLING DEVICE AND USE THEREOF FOR FILLING A FLUID MERCK PATENT GMBH (DE) 2018-02-21 EP disclosed
EP-2691490-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-07-26 EP disclosed
EP-2628779-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-05-17 EP disclosed
CN-101501099-B Polymer having bis(diphenylphosphino)binaphthyl group KYOEISHA CHEMICAL CO LTD 2011-10-05 CN disclosed
CN-101501099-A Polymer having bis(diphenylphosphino)binaphthyl group KYOEISHA CHEMICAL CO LTD (JP) 2009-08-05 CN disclosed