Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18871330 | 0.88 | MRGPRX4 (0.39) | HTR6MRGPRX4NR1H4ALDH1A1S1PR1 | |
| SCHEMBL18831656 | 0.85 | GRM5 (0.38) | MRGPRX4ALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL18831406 | 0.82 | MRGPRX4 (0.35) | MRGPRX4 | |
| SCHEMBL18831746 | 0.81 | SLC22A12 (0.37) | MRGPRX4ALDH1A1SLC22A12SMN1; SMN2NPC1 | |
| SCHEMBL18871617 | 0.80 | HTR6 (0.35) | HTR6MRGPRX4NR1H4S1PR1S1PR5 | |
| SCHEMBL20686779 | 0.79 | PTGDR2 (0.35) | HTR6MRGPRX4L3MBTL1 | |
| SCHEMBL18871267 | 0.79 | SLC22A12 (0.33) | HTR6SLC22A12MAPTRAB9ATHRB | |
| SCHEMBL18831547 | 0.79 | MAOA (0.37) | MRGPRX4ALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL18831649 | 0.79 | SLC22A12 (0.39) | MRGPRX4NR1H4ALDH1A1SLC22A12SMN1; SMN2 | |
| SCHEMBL20195507 | 0.79 | SSTR4 (0.37) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900654-B1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2017-05-17 | — | — | EP | disclosed |