Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13640179 | 0.81 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KMT2AMAPTTP53 | |
| SCHEMBL11109819 | 0.76 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KMT2AMAPTTP53 | |
| SCHEMBL12829890 | 0.76 | KDM4E (0.56) | ALDH1A1SMN1; SMN2KMT2AMAPTTP53 | |
| SCHEMBL13640156 | 0.74 | BUB1 (0.45) | ALDH1A1SMN1; SMN2KMT2AMAPTHPGD | |
| SCHEMBL18871411 | 0.72 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2KMT2AMAPTTP53 | |
| SCHEMBL22056805 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTTP53HTT | |
| SCHEMBL13640438 | 0.71 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KMT2AMAPTHTT | |
| SCHEMBL13640182 | 0.71 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2KMT2AMAPTTP53 | |
| SCHEMBL18595077 | 0.70 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KMT2ATP53HPGD | |
| SCHEMBL12646547 | 0.70 | MAPT (0.51) | ALDH1A1SMN1; SMN2MAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477491-B1 | PLANT ADDITIVES AND USES THEREOF TO MODULATE THE SYNTHESIS OF MEMBRANE GLYCEROLIPIDS IN PLANTS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-05-17 | — | — | EP | disclosed |