SCHEMBL13640156

SCHEMBL13640156

Cc1c(Cl)cccc1NC=C1C(=O)CC(C)(C)CC1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BUB1 O43683 3/20 0.45
▸ MAPT P10636 3/20 0.39
▸ ALDH1A1 P00352 4/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ SMN1; SMN2 Q16637 3/20 0.37
▸ LMNA P02545 2/20 0.37
▸ RECQL P46063 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ USP2 O75604 1/20 0.37
▸ MT-CO2 P00403 1/20 0.37
▸ TTR P02766 1/20 0.37
▸ PLA2G1B P04054 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ PGR P06401 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ HTR1A P08908 1/20 0.37
▸ ADRA2A P08913 1/20 0.37
▸ ADORA3 P0DMS8 1/20 0.37
▸ AR P10275 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18871411 0.78 ALDH1A1 (0.34) MAPTALDH1A1KMT2ASMN1; SMN2LMNA
SCHEMBL13640179 0.75 ALDH1A1 (0.42) MAPTALDH1A1KMT2ASMN1; SMN2LMNA
SCHEMBL18871544 0.74 ALDH1A1 (0.41) MAPTALDH1A1KMT2ASMN1; SMN2LMNA
SCHEMBL13640458 0.73 MEN1 (0.46) BUB1MAPTALDH1A1KMT2ALMNA
SCHEMBL11887914 0.73 KDR (0.50) MAPTALDH1A1KMT2ASMN1; SMN2LMNA
SCHEMBL13640140 0.72 PKM (0.46) BUB1MAPTALDH1A1KMT2ASMN1; SMN2
SCHEMBL22056805 0.72 ALDH1A1 (0.43) BUB1MAPTALDH1A1KMT2ARECQL
SCHEMBL22057718 0.72 MAOA (0.45) BUB1MAPTALDH1A1KMT2ASMN1; SMN2
SCHEMBL13640143 0.71 ALDH1A1 (0.46) BUB1MAPTALDH1A1KMT2ASMN1; SMN2
SCHEMBL13640438 0.71 ALDH1A1 (0.44) MAPTALDH1A1KMT2ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2477491-B1 PLANT ADDITIVES AND USES THEREOF TO MODULATE THE SYNTHESIS OF MEMBRANE GLYCEROLIPIDS IN PLANTS COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-05-17 — — EP disclosed
US-9028855-B2 Plant additives and uses thereof to modulate the synthesis of membrane glycerolipids in planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-05-12 — — US disclosed
US-9028855-B2 Plant additives and uses thereof to modulate the synthesis of membrane glycerolipids in planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-05-12 — — US disclosed
US-20120283101-A1 Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2012-11-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120283101-A1 Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta PGM2, SGMS2, PHOSPHO1 BUB1 3024/4885MAPT 4242/4885ALDH1A1 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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