Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | BUB1 | O43683 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.44 |
| ▸ | RELA | Q04206 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27945041 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL13640179 | 0.80 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL18871544 | 0.76 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL11109819 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2RAB9AHSD17B10 | |
| SCHEMBL13640156 | 0.71 | BUB1 (0.45) | ALDH1A1BUB1MAPTSMN1; SMN2HPGD | |
| SCHEMBL2612359 | 0.69 | KDM4E (0.58) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL18871411 | 0.69 | ALDH1A1 (0.34) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL18871126 | 0.69 | KDM4E (0.51) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL8428005 | 0.68 | MAPT (0.51) | KDM4EALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL13640189 | 0.68 | NTRK3 (0.43) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477491-B1 | PLANT ADDITIVES AND USES THEREOF TO MODULATE THE SYNTHESIS OF MEMBRANE GLYCEROLIPIDS IN PLANTS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-05-17 | — | — | EP | disclosed |
| US-9028855-B2 | Plant additives and uses thereof to modulate the synthesis of membrane glycerolipids in planta | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-05-12 | — | — | US | disclosed |
| US-9028855-B2 | Plant additives and uses thereof to modulate the synthesis of membrane glycerolipids in planta | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-05-12 | — | — | US | disclosed |
| US-20120283101-A1 | Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-11-08 | — | — | US | disclosed |
| US-20120283101-A1 | Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-11-08 | — | — | US | disclosed |
| EP-2301347-A1 | Plant additives and uses thereof to modulate the synthesis of membrane glycerolipids in planta | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2011-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283101-A1 | Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta | PGM2, SGMS2, PHOSPHO1 | KDM4E 4287/4885ALDH1A1 3248/4885BUB1 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.