Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Proline SCHEMBL7043240 | 0.91 | NOS2 (0.33) | NOS2NOS3NOS1CYP3A4CYP2D6 | |
| Threonine SCHEMBL7041488 | 0.91 | NOS2 (0.33) | NOS2NOS3NOS1CYP3A4CYP2D6 | |
| Leucine SCHEMBL6463328 | 0.90 | SLC7A5 (0.44) | NOS2NOS3NOS1CYP3A4CYP2D6 | |
| Glutamine SCHEMBL1304983 | 0.87 | KMT2A (0.43) | NOS2NOS3NOS1CYP3A4CYP2D6 | |
| SCHEMBL527857 | 0.84 | TLR2 (0.35) | CYP3A4CYP2D6CYP1A2CYP2C19PRCP | |
| SCHEMBL10955255 | 0.82 | NOS2 (0.41) | NOS2NOS3NOS1CYP3A4CYP2D6 | |
| SCHEMBL8815155 | 0.81 | TLR2 (0.31) | TLR2 | |
| SCHEMBL442337 | 0.80 | P2RY10 (0.37) | NOS2NOS3NOS1CYP3A4CYP2D6 | |
| Valine SCHEMBL2118868 | 0.79 | SLC7A5 (0.37) | NOS2NOS3NOS1SLC7A5 | |
| SCHEMBL7782161 | 0.79 | PRCP (0.41) | NOS2NOS3NOS1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537171-A4 | CD46 VARIANTS | — | 1993-06-30 | — | — | EP | claimed |
| EP-0537171-A1 | CD46 VARIANTS | THE AUSTIN RESEARCH INSTITUTE (AU) | 1993-04-21 | — | — | EP | claimed |
| WO-1991018097-A1 | CD46 VARIANTS | UNIVERSITY OF MELBOURNE (AU) | 1991-11-28 | — | — | WO | claimed |
| US-20240207407-A1 | EGFRVIII BINDING PROTEINS | Myrio Therapeutics Pty Ltd (AU) | 2024-06-27 | — | — | US | disclosed |
| WO-2024124286-A1 | THERAPEUTIC EXTRACELLULAR VESICLES | THE UNIVERSITY OF NEWCASTLE (AU) | 2024-06-20 | — | — | WO | disclosed |
| EP-3793586-B1 | SOLUBLE COMPLEMENT RECEPTOR TYPE 1 VARIANTS AND USES THEREOF | CSL LTD (AU) | 2024-04-10 | — | — | EP | disclosed |
| EP-4330285-A1 | EGFRVIII BINDING PROTEINS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2024-03-06 | — | — | EP | disclosed |
| WO-2024038407-A1 | LIPID NANOPARTICLE COMPRISING A DNA-BINDING PROTEIN | Seqirus Inc. (US) | 2024-02-22 | — | — | WO | disclosed |
| US-20230399376-A1 | BINDING PROTEINS COMPRISING THE EXTRACELLULAR DOMAIN OF CD39 AND METHODS OF TREATING OR PREVENTING NEUROLOGICAL DISEASES | BAKER HEART AND DIABETES INST (AU) | 2023-12-14 | — | — | US | disclosed |
| WO-2022226584-A1 | EGFRvIII BINDING PROTEINS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2022-11-03 | — | — | WO | disclosed |
| US-20220305133-A1 | Soluble Complement Receptor Type 1 Variant Conjugates and Uses Thereof | CSL Innovation Pty., Ltd. (AU) | 2022-09-29 | — | — | US | disclosed |
| WO-2002074996-A1 | GENE REGULATION | GENDAQ LIMITED (GB) | 2002-09-26 | — | — | WO | disclosed |
| EP-1234185-A2 | PIN1 AS A MARKER FOR ABNORMAL CELL GROWTH | Beth Israel Deaconess Medical Center (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2002057308-A2 | ZINC FINGER POLYPEPTIDES AND THEIR USE | SANGAMO BIOSCIENCES, INC. (US) | 2002-07-25 | — | — | WO | disclosed |
| WO-2002004488-A2 | NUCLEIC ACID BINDING POLYPEPTIDES | SANGAMO BIOSCIENCES, INC. (US) | 2002-01-17 | — | — | WO | disclosed |
| WO-2001085780-A2 | NUCLEIC ACID BINDING POLYPEPTIDES | GENDAQ LIMITED (GB) | 2001-11-15 | — | — | WO | disclosed |
| US-6303357-B1 | HEAT STABLE ENZYMATIC POLYPEPTIDE; FOR USE AS A DIAGNOSTIC TOOL IN MEASUREMENT OF LIPASE ACTIVITY AND DETERMINATION OF TRIGLYCERIDE, GLYCEROL, ADENOSINE TRIPHOSPHATE CONCENTRATIONS | AMANO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-16 | — | — | US | disclosed |
| EP-1138769-A1 | Recombinant L-alpha-glycerophosphate oxidase gene, and method for producing the same | AMANO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-04 | — | — | EP | disclosed |
| WO-2001053480-A1 | NUCLEIC ACID BINDING POLYPEPTIDES CHARACTERIZED BY FLEXIBLE LINKERS CONNECTED NUCLEIC ACID BINDING MODULES | SANGAMO BIOSCIENCES, INC. (US) | 2001-07-26 | — | — | WO | disclosed |
| WO-2001038878-A2 | PIN1 AS A MARKER FOR ABNORMAL CELL GROWTH | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2001-05-31 | — | — | WO | disclosed |