Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1887227 | 0.90 | NOS2 (0.40) | SLC7A5SLC1A3SLC1A2SLC1A1PRCP | |
| Leucine SCHEMBL1479587 | 0.87 | SLC7A5 (0.49) | SLC7A5SLC1A3SLC1A2SLC1A1PRCP | |
| Leucine SCHEMBL1479588 | 0.87 | SLC7A5 (0.49) | SLC7A5SLC1A3SLC1A2SLC1A1PRCP | |
| Glutamine SCHEMBL1304983 | 0.85 | KMT2A (0.43) | SLC1A3SLC1A2SLC1A1PRCPNOS2 | |
| SCHEMBL527857 | 0.83 | TLR2 (0.35) | PRCPCYP1A2CYP3A4CYP2D6CYP2C19 | |
| D-Leucine SCHEMBL1537225 | 0.82 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1PRCP | |
| Leucine SCHEMBL139231 | 0.82 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1PRCP | |
| Leucine SCHEMBL756554 | 0.82 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1PRCP | |
| Leucine SCHEMBL17113857 | 0.82 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1PRCP | |
| Leucine SCHEMBL139230 | 0.82 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050089910-A1 | DNA polymerase having ability to reduce innate selective discrimination against fluorescent dye-labeled dideoxynucleotides | HONG GUOFAN (CN) | 2005-04-28 | — | — | US | disclosed |
| US-6818431-B1 | RESISTANT TO HEAT INACTIVATION/IMPROVED INCORPORATION; FOR AUTOMATED TERMINATOR DNA SEQUENCING | SHANGHAI MENDEL DNA CENTER CO. LTD. (CN) | 2004-11-16 | — | — | US | disclosed |
| US-6485909-B1 | DNA polymerase having ability to reduce innate selective discrimination against fluorescent dye-labeled dideoxynucleotides | SHANGHAI MENDEL DNA CENTER CO., LTD. (CN) | 2002-11-26 | — | — | US | disclosed |
| EP-1115848-A4 | DNA POLYMERASE HAVING ABILITY TO REDUCE INNATE SELECTIVE DISCRIMINATION AGAINST FLUORESCENT DYE-LABELED DIDEOXYNUCLEOTIDES | SHANGHAI INST BIOCHEMISTRY (CN) | 2002-08-21 | — | — | EP | disclosed |
| EP-1115848-A1 | DNA POLYMERASE HAVING ABILITY TO REDUCE INNATE SELECTIVE DISCRIMINATION AGAINST FLUORESCENT DYE-LABELED DIDEOXYNUCLEOTIDES | Shanghai Institute of Biochemistry Chinese Academy of Sciences (CN) | 2001-07-18 | — | — | EP | disclosed |
| US-6165765-A | DNA polymerase having ability to reduce innate selective discrimination against fluorescent dye-labeled dideoxynucleotides | SHANGHAI INSTITUTE OF BIOCHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2000-12-26 | — | — | US | disclosed |
| WO-2000017330-A1 | DNA POLYMERASE HAVING ABILITY TO REDUCE INNATE SELECTIVE DISCRIMINATION AGAINST FLUORESCENT DYE-LABELED DIDEOXYNUCLEOTIDES | SHANGAI INSTITUTE OF BIOCHEMISTRY CHINESE ACADEMY OF SCIENCES (US) | 2000-03-30 | — | — | WO | disclosed |