Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | TPO | P07202 | 1/20 | 0.39 |
| ▸ | EPX | P11678 | 1/20 | 0.39 |
| ▸ | LPO | P22079 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610781 | 0.81 | MCHR1 (0.38) | KDM4EHSD17B10NOS3NOS2MPO | |
| SCHEMBL17471316 | 0.81 | NOS3 (0.45) | KDM4EHSD17B10NOS3NOS2MPO | |
| SCHEMBL16964110 | 0.79 | MPO (0.37) | KDM4EHSD17B10NOS3NOS2MPO | |
| SCHEMBL13835368 | 0.77 | ACVR1 (0.41) | KDM4EHSD17B10MPOTPOEPX | |
| SCHEMBL29603339 | 0.73 | ALOX5AP (0.49) | HSD17B10NOS3NOS2MPOTPO | |
| SCHEMBL2305476 | 0.73 | ALOX5AP (0.49) | HSD17B10NOS3NOS2MPOTPO | |
| Hydrochloric Acid SCHEMBL27039157 | 0.72 | ALOX5AP (0.48) | KDM4EHSD17B10NOS3NOS2MPO | |
| SCHEMBL7099252 | 0.71 | CHRNB2 (0.45) | KCNH2 | |
| SCHEMBL625665 | 0.71 | KDM4E (0.40) | KDM4EHSD17B10NOS3NOS2MPO | |
| SCHEMBL30699249 | 0.71 | KDM4E (0.40) | KDM4EHSD17B10NOS3NOS2MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600810-A | Dihydrofuranopyridine derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2023-08-15 | — | — | CN | disclosed |
| EP-2744804-B1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN LA ROCHE (CH) | 2017-05-17 | — | — | EP | disclosed |