Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.38 |
| ▸ | C5 | P01031 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561524 | 0.86 | LPAR1 (0.53) | CHEK1LPAR1NPC1RAB9A | |
| SCHEMBL18874043 | 0.80 | LPAR1 (0.48) | LPAR1SIGMAR1NPC1RAB9APOLB | |
| SCHEMBL18874186 | 0.79 | LPAR1 (0.49) | LPAR1SIGMAR1NPC1RAB9APOLB | |
| SCHEMBL18874338 | 0.79 | LPAR1 (0.47) | LPAR1SIGMAR1NPC1RAB9APOLB | |
| SCHEMBL18873947 | 0.79 | LPAR1 (0.47) | LPAR1SIGMAR1NPC1RAB9APOLB | |
| SCHEMBL18874173 | 0.78 | LPAR1 (0.46) | LPAR1C5SIGMAR1NPC1RAB9A | |
| SCHEMBL18874419 | 0.78 | HPGD (0.39) | CHEK1HPGDLPAR1C5PPARG | |
| SCHEMBL18873914 | 0.77 | POLB (0.48) | LPAR1SIGMAR1POLBALDH1A1 | |
| SCHEMBL18874318 | 0.77 | LPAR1 (0.46) | LPAR1C5SIGMAR1NPC1RAB9A | |
| SCHEMBL18873889 | 0.77 | LPAR1 (0.46) | LPAR1SIGMAR1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |