Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.38 |
| ▸ | C5 | P01031 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561377 | 0.86 | LPAR1 (0.53) | HPGDLPAR1NPC1RAB9A | |
| SCHEMBL18874043 | 0.79 | LPAR1 (0.48) | LPAR1NPC1RAB9APOLB | |
| SCHEMBL18874338 | 0.78 | LPAR1 (0.47) | LPAR1NPC1RAB9APOLB | |
| SCHEMBL18874186 | 0.78 | LPAR1 (0.49) | LPAR1NPC1RAB9APOLB | |
| SCHEMBL18873889 | 0.78 | LPAR1 (0.46) | LPAR1ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL18873939 | 0.78 | CHEK1 (0.41) | HPGDLPAR1C5ALDH1A1PPARG | |
| SCHEMBL18873947 | 0.78 | LPAR1 (0.47) | LPAR1NPC1RAB9APOLB | |
| SCHEMBL18874194 | 0.77 | LPAR1 (0.60) | LPAR1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL18874173 | 0.77 | LPAR1 (0.46) | LPAR1C5NPC1RAB9APOLB | |
| SCHEMBL18873914 | 0.76 | POLB (0.48) | LPAR1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |