SCHEMBL18874103

SCHEMBL18874103

Cc1csc(-c2ccc(-c3ccc(-c4cc(C)cs4)s3)s2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.37
ESR2 Q92731 1/20 0.34
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
GHSR Q92847 2/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
GFER P55789 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2E1 P05181 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C8 P10632 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2A6 P11509 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP4B1 P13584 1/20 0.32
CYP2B6 P20813 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18517201 1.00 DAO (0.37) DAOESR2HSD17B1HSD17B2GHSR
SCHEMBL10471752 0.91 ALDH1A1 (0.46) DAONPC1ALDH1A1MAPTGFER
SCHEMBL12031412 0.89 ALDH1A1 (0.47) DAOGHSRNPC1ALDH1A1MAPT
SCHEMBL9773308 0.87 DAO (0.44) DAOKDM5BTDP2HDAC3HDAC1
SCHEMBL10472855 0.86 HSD17B1 (0.47) HSD17B1HSD17B2NPC1ALDH1A1MAPT
SCHEMBL10471660 0.86 DPP4 (0.47) NPC1ALDH1A1MAPTHSD17B10CYP1A2
SCHEMBL16638257 0.82 KMT2A (0.35) DAONPC1
SCHEMBL29958015 0.80 TSHR (0.38) DAO
SCHEMBL15724612 0.77 PTGS2 (0.37) ALDH1A1HSD17B10CYP3A4
SCHEMBL3694756 0.77 APP (0.42) HSD17B1HSD17B2GHSRCYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2626375-B1 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2017-11-22 EP disclosed
US-9650461-B2 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2017-05-16 US disclosed