Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCYL1 | O43865 | 3/20 | 0.70 |
| ▸ | AHCY | P23526 | 12/20 | 0.51 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ADA | P00813 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18878461 | 0.84 | AHCYL1 (0.80) | AHCYL1AHCYEZH2SMN1; SMN2ADA | |
| SCHEMBL17532522 | 0.82 | AHCYL1 (1.00) | AHCYL1AHCYEZH2SMN1; SMN2ADA | |
| SCHEMBL17532524 | 0.82 | AHCYL1 (1.00) | AHCYL1AHCYEZH2SMN1; SMN2ADA | |
| SCHEMBL17532525 | 0.82 | AHCYL1 (0.67) | AHCYL1AHCYEZH2SMN1; SMN2 | |
| SCHEMBL863322 | 0.69 | AHCY (0.69) | AHCYL1AHCYEZH2SMN1; SMN2 | |
| SCHEMBL29308157 | 0.69 | AHCY (0.80) | AHCYL1AHCYEZH2SMN1; SMN2 | |
| SCHEMBL12322150 | 0.68 | AHCY (0.70) | AHCYL1AHCYEZH2SMN1; SMN2 | |
| 3-Deazaneplanocin A SCHEMBL23683021 | 0.68 | AHCY (1.00) | AHCYL1AHCYEZH2SMN1; SMN2 | |
| 3-Deazaneplanocin A SCHEMBL18256281 | 0.68 | AHCY (1.00) | AHCYL1AHCYEZH2SMN1; SMN2 | |
| 3-Deazaneplanocin A SCHEMBL1521229 | 0.68 | AHCY (1.00) | AHCYL1AHCYEZH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657048-B2 | Enantiomers of the 1′,6′-isomer of neplanocin A | AUBURN UNIVERSITY (US) | 2017-05-23 | — | — | US | disclosed |