Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCYL1 | O43865 | 3/20 | 0.80 |
| ▸ | AHCY | P23526 | 11/20 | 0.48 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532522 | 0.89 | AHCYL1 (1.00) | AHCYL1AHCYEZH2SMN1; SMN2ADA | |
| SCHEMBL17532524 | 0.89 | AHCYL1 (1.00) | AHCYL1AHCYEZH2SMN1; SMN2ADA | |
| SCHEMBL18878460 | 0.84 | AHCYL1 (0.70) | AHCYL1AHCYEZH2SMN1; SMN2ADA | |
| SCHEMBL17532525 | 0.79 | AHCYL1 (0.67) | AHCYL1AHCYEZH2SMN1; SMN2 | |
| SCHEMBL18878458 | 0.76 | AHCYL1 (0.81) | AHCYL1AHCY | |
| SCHEMBL18878459 | 0.72 | AHCYL1 (0.72) | AHCYL1AHCYEZH2ADA | |
| SCHEMBL29308157 | 0.69 | AHCY (0.80) | AHCYL1AHCYEZH2SMN1; SMN2 | |
| SCHEMBL17501761 | 0.68 | AHCYL1 (0.65) | AHCYL1AHCYSMN1; SMN2 | |
| SCHEMBL29361147 | 0.68 | AHCYL1 (0.65) | AHCYL1AHCYSMN1; SMN2 | |
| SCHEMBL17501744 | 0.68 | AHCYL1 (0.65) | AHCYL1AHCYSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657048-B2 | Enantiomers of the 1′,6′-isomer of neplanocin A | AUBURN UNIVERSITY (US) | 2017-05-23 | — | — | US | disclosed |