Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18878692 | 0.85 | GAA (0.52) | CASP2NAAAEPHX1GAA | |
| SCHEMBL7343085 | 0.83 | CASP2 (0.64) | CASP2NAAAEPHX1GAAFAAH | |
| SCHEMBL8183109 | 0.83 | S1PR2 (0.50) | CASP2NAAAEPHX1GAA | |
| SCHEMBL29255848 | 0.83 | CASP2 (0.64) | CASP2NAAAEPHX1GAAFAAH | |
| SCHEMBL17740223 | 0.80 | CASP2 (0.70) | CASP2NAAAEPHX1FAAHEPHX2 | |
| SCHEMBL5313764 | 0.79 | GAA (0.58) | CASP2EPHX1GAA | |
| SCHEMBL24427125 | 0.78 | HSP90AA1 (0.55) | CASP2NAAAEPHX1FAAH | |
| SCHEMBL19703839 | 0.78 | CASP2 (0.68) | CASP2NAAAEPHX1FAAHEPHX2 | |
| SCHEMBL24240988 | 0.77 | HDAC1 (0.44) | CASP2EPHX1GAAFAAH | |
| SCHEMBL19400435 | 0.77 | CASP2 (0.71) | CASP2NAAAEPHX1FAAHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170146549-A1 | ISOBARIC MASS LABELS | ELECTROPHORETICS LIMITED (GB) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170146549-A1 | ISOBARIC MASS LABELS | SRMS, PTMS, QPCTL | CASP2 2600/4885NAAA 2738/4885EPHX1 1078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.